Boc-NH-PEG12-CH2CH2COOHCan be used to produce therapeutic products, radioactive grade, up to 99% pure.Ph-sensitive BOC-PEG micelle carriers contain a large number of easily dissociated or protonated acidic groups (e.g. -COOH) and basic groups (e.g. -NH2). The ionization degree of the group changes with the pH value of the solution, resulting in a corresponding change in the conformation of the molecular chain. Since the pH of normal human tissue environment is about 7.4, and for solid tumor tissue, most pH values are about 7.0, the pH response of boC-PEG micelles is best at 7.0.
Boc-NH-PEG12-CH2CH2COOHCan be used to produce therapeutic products, radioactive grade, up to 99% pure.Ph-sensitive BOC-PEG micelle carriers contain a large number of easily dissociated or protonated acidic groups (e.g. -COOH) and basic groups (e.g. -NH2). The ionization degree of the group changes with the pH value of the solution, resulting in a corresponding change in the conformation of the molecular chain. Since the pH of normal human tissue environment is about 7.4, and for solid tumor tissue, most pH values are about 7.0, the pH response of boC-PEG micelles is best at 7.0.
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