Polyethylene glycols is used in a wide range of biomedical applications including drug delivery, ADC conjugation, fluorescent labeling & targeted diagnostics, oligonucleotides bioconjugation, surface modification and PEGylation of protein &peptide.
PEG derivatives used as drug target by direct therapeutic PEGylation containing vehicles such as liposomes micelles, nanoparticles, dendrimers and can link together antibody-drug conjugates (ADCs) for many kinds of illnesses. PEG as the compound, also can be used to bioconjugate itself to the target, by coupling itself with the target molecule to optimize the pharmacokinetic properties of drug treatment or as a surface coating on nanoparticles to enhance systemic drug delivery.
There will be more medical applications of PEG in the future. Now we focus on exploring and research how PEG can be used in peptidesThe world's first long-acting HIV fusion inhibitor
Pukang is the designated supplier of the drug's PEG-focused intermediate.