Views: 0 Author: Site Editor Publish Time: 2021-11-16 Origin: Site
Diabetes is a group of metabolic diseases characterized by hyperglycemia. Hyperglycaemia, in turn, is caused by a defect in insulin secretion or impairment of its biological activity, or both. The prolonged presence of hyperglycemia leads to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. As living conditions improve, more and more people are suffering from this disease. However, Fmoc-PEG is one of the active ingredients in the drugs used to treat diabetes. So do you know what the advantages of Fmoc-PEG are?
Here is the content list:
•Modifier technical grade small molecules
•Polyethylene glycol modification
•More chemically stable
Modifier technical grade small molecular
Experts point out that Modifier technical grade small molecule has the potential to expand into a large industry, where there is nutrition, there are small molecules and Modifier technical grade small molecule is used, it will drive the upgrading of the pharmaceutical and nutrition industries. The use of this technology for medical intermediates is undoubtedly more popular. This is because it makes it easier for patients to absorb drugs into their bodies and thus has a greater effect. And Fmoc-PEG uses this technology.
Polyethylene glycol modification
The benefits of Fmoc-PEG, a compound modified with polyethylene glycol, in the treatment of diabetes include reduced renal and cellular clearance and prolonged half-life; enhanced protection against protein hydrolysis; and reduced toxicity. It allows for the increased biological activity of Fmoc-PEG and improved pharmacokinetic and pharmacodynamic properties while retaining the intrinsic biological activity of the natural components. Optimization of the pharmacokinetics and pharmacodynamics of polyethylene glycol proteins is required to improve pharmacological activity and clinical efficacy, and the structure, length, molecular weight, and modification methods of PEG polymer chains are all factors that influence this optimization. For-PEG is, therefore, a highly effective ingredient.
More chemically stable
A major advantage of Fmoc-PEG, due to its Fmoc protecting group, is that it is extremely stable to acids and in its presence, Boc and benzyl groups can be deprotected. Other advantages of Fmoc are that it is more easily deprotected by simple amines without hydrolysis, allowing the protected amine to be released as a free base. Fmoc-PEG is generally stable to hydrogenation and the Fmoc protecting group of Fmoc-PEG can be paired with an acid-removed protecting group for peptide synthesis in both liquid and solid phases. Furthermore, Fmoc-PEG is Therapeutic high purity.
The increasing number of people with diabetes is related to social development and lifestyle changes. For-PEG is a pharmaceutical intermediate for the treatment of diabetes and is widely used in this field. Fmoc-PEG is a pharmaceutical intermediate for the treatment of diabetes and is widely used in this field, therefore its medical and commercial value is very high. If you need Fmoc-PEG, you can consider our cost-effective products. Chengdu Pukang Biotechnology Co., Ltd are non-toxic and tasteless, perfect after-sales service, you can have no worries. Chengdu Pukang Biotechnology Co., Ltd was founded in 2008 and it is located in the national cross-strait science and technology industry development park——Cross-Strait Science and Technology Park, Wenjiang District, Chengdu,specializing in the long-term development of peptide drugs for chronic disease.